Advances in Virus Research. Bacteriophages, part A. Preface. - PubMed - NCBI
A new world of possibilities for "virus discovery" was opened up with high-throughput sequencing becoming available in the last decade. While scientifically metagenomic analysis was established before the start of the era of high-throughput sequencing, the availability of the first second-generation sequencers was the kick-off for diagnosticians to use sequencing for the detection of novel pathogens. Today, diagnostic metagenomics is becoming the standard procedure for the detection and genetic characterization of new viruses or novel virus variants Bluetongue virus is transmitted between its ruminant hosts by the bite of Culicoides spp.
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Severe BT cases are characterized by symptoms including hemorrhagic fever, particularly in sheep, loss of productivity, and death. To date, 27 BTV serotypes have been documented. These include novel isolates of atypical BTV, which have been almost fully characterized using deep sequencing technologies and do not rely on Culicoides vectors for their transmission among hosts New Leaves in the Growing Tree of Pestiviruses.
Pestiviruses are a group of viruses of veterinary importance infecting livestock animals like pigs, cattle, and sheep, and also wildlife animals like wild boar and different deer species. While for decades only four classical species Classical swine fever virus, Bovine viral diarrhea virus types 1 and 2, Border disease virus , and a few so-called atypical pestiviruses were known e.
Astroviruses are best known as being one of the leading causes of diarrhea in infants and were first described in this context in In its first years, astrovirus research was mainly restricted to electron microscopy and serology studies.
The ability to culture some of these viruses in vitro allowed a first consequent step forward, especially at the molecular level. Since the emergence of more powerful genetic methods, though, the face of this research field has dramatically changed and evolved. From the exponential number of discoveries of new astrovirus strains in the most varied of animal species to their association with atypical diseases, these viruses revealed a lot of surprises, and many more are probably still waiting to be uncovered The First "Virus Hunters". The history of virology is a history of conceptual and technological inventions and breakthroughs.
The development of filters made of porcelain or kieselgur by the end of the 19th century which withheld bacteria allowed the identification of infectious agents smaller than bacteria and noncultivable on the media known at that time and used to grow bacteria. Even finer-grain filters resulted in the observation that the ultravisible novel infectious agents are in fact of particulate nature.
Infections of plants and animals were the first to be attributed to these tiny entities The Envelope Proteins of the Bunyavirales. The Bunyavirales Order encompasses nine families of enveloped viruses containing a single-stranded negative-sense RNA genome divided into three segments.
The small S and large L segments encode proteins participating in genome replication in the infected cell cytoplasm. The middle M segment encodes the viral glycoproteins Gn and Gc, which are derived from a precursor polyprotein by host cell proteases. Entry studies are available only for a few viruses in the Order, and in each case they were shown to enter cells via receptor-mediated endocytosis Illuminating the virus life cycle with single-molecule FRET imaging.
The application of atomic force microscopy for viruses and protein shells: Imaging and spectroscopy. The viral replication organelles within cells studied by electron microscopy. Entry of bunyaviruses into plants and vectors.
Hantavirus entry: Perspectives and recent advances. Key checkpoints in the movement of plant viruses through the host.
ISBN 13: 9780128047361
Gammaherpesvirus entry and fusion: A tale how two human pathogenic viruses enter their host cells. Coronaviruses, the latest volume in the Advances in Virus Research series first published in , covers a diverse range of in-depth reviews, providing a valuable overview of the field. This series is a valuable resource for virologists, microbiologists, immunologists, molecular biologists, pathologists, and plant researchers. Convert currency. Add to Basket. Book Description Academic Press, Condition: New.
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